Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 31 - 40 of 95 |
Principal Clinical Data Manager
Cambridge, Massachusetts
Overview: The Principal Clinical Data Manager, Data Management will lead and contribute to data management activities in support of Alnylam studies across all stages of clinical drug development. This position reports to the Director, Data ...
12h
| Job Type | Full Time |
Principal Associate Scientist, Analytical Sciences
Cambridge, Massachusetts
NOTICE OF FILING AN APPLICATION FOR PERMANENT EMPLOYMENT CERTIFICATION JOB TITLE: Principal Associate Scientist (Multiple Positions) JOB DUTIES: Perform analytical testing of siRNA drug substances, drug products, and critical raw materials....
12h
| Job Type | Full Time |
Medical Science Liaison - North Central (MI & IN)
Indianapolis, Indiana
Overview: We are seeking an experienced Medical Science Liaison (MSL) to join the TTR team and support Alnylam's commitment to advancing the science and care of patients with transthyretin (TTR) amyloidosis. Patients often experience prolon...
12h
| Job Type | Full Time |
Medical Science Liaison - North Central (MI & IN)
Detroit, Michigan
Overview: We are seeking an experienced Medical Science Liaison (MSL) to join the TTR team and support Alnylam's commitment to advancing the science and care of patients with transthyretin (TTR) amyloidosis. Patients often experience prolon...
12h
| Job Type | Full Time |
Medical Director, Clinical Research
Philadelphia, Pennsylvania
Overview Alnylam Pharmaceuticals is seeking an imaginative physician drug developer, with the flexibility and confidence to work in therapeutic areas that may be beyond their particular expertise or experience. This is an opportunity to pro...
12h
| Job Type | Full Time |
Medical Director, Clinical Research
Cambridge, Massachusetts
Overview Alnylam Pharmaceuticals is seeking an imaginative physician drug developer, with the flexibility and confidence to work in therapeutic areas that may be beyond their particular expertise or experience. This is an opportunity to pro...
12h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Manager, Nonclinical Writing provides nonclinical submission support for scientific staff. This individual will represent Nonclinical Writing on project teams, working directly with scientists within the Early Development (eDEV...
12h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Manager, Logistics Design & Cold Chain will support the development, implementation, and continuous improvement of global logistics design standards to help ensure product integrity across Alnylam's end-to-end supply chain netw...
12h
| Job Type | Full Time |
Manager, CMC Project Management
Cambridge, Massachusetts
Overview This role will partner with CMC Technical Leads to drive the planning, coordination, and execution of complex CMC development programs across the Technical Operations and Quality (TOQ) organization. The role serves as the operation...
12h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Early Development and Research Departments at Alnylam are seeking a Lab Operations Associate to join our team to support the Sample Management group in the receiving and storage of clinical and nonclinical samples. We are seeki...
12h
| Job Type | Full Time |