VP, Global Medical Affairs

COMPANY:

At BioCryst, we share a deep commitment to improving the lives of people living with complement-mediated and other rare diseases. For over three decades we've been guided by our passion for not settling for "ordinary" in our quest to develop novel medicines. We leverage our expertise in structure-guided drug design to develop first-in-class or best-in-class oral small-molecule and protein therapeutics, led by the efforts of our team of expert scientists in our Discovery Center of Excellence in Birmingham, Alabama. Our global headquarters is in Durham, North Carolina and our employees span the globe across sites in multiple countries. We are proud of our culture of engagement and accountability that rewards people for innovative thinking and achievement of key objectives. For more information, please visit our website at www.biocryst.com or follow uson LinkedIn and Instagram.

JOB SUMMARY:

We are seeking an experienced and agile Head of Global Medical Affairs, reporting to the Chief Data Innovation Officer to lead our global medical affairs function. This role is central to leading our medical strategy within the context of BioCryst business priorities, while ensuring seamless execution across field medical, publications, and operational functions.

Building on BioCryst's strong foundation, this leader will leverage existing strengths and infrastructure to drive innovation, enhance productivity, and deliver exceptional value to the organization. Success in this role requires a balance of strategic insight, creative problem-solving, relentless collaboration, and disciplined execution-fostering scientific excellence, compliance, and meaningful engagement with internal and external stakeholders. #LI-Remote

The ideal candidate:

• Thrives in a dynamic environment and brings agility to navigate ambiguity.
• Inspires and empowers teams, cultivating collaboration and high performance.
• Champions innovation while respecting established processes and compliance standards.
• Ensures cross-functional alignment, partnering effectively across the enterprise to achieve shared goals.
• Demonstrates strong business acumen, aligning short- and long-term medical strategy with organizational priorities and driving measurable impact.

ESSENTIAL DUTIES & RESPONSIBILITIES:

Leadership & Strategy

• Lead and evolve the Medical Affairs strategy in alignment with corporate objectives and product lifecycle needs.
• Build and manage a high-impact MSL team, ensuring scientific engagement excellence and field insights generation.
• Oversee the development and execution of scientific publication plans and medical communications.
• Drive operational excellence across Medical Affairs, including budget management, systems, and process optimization.

Cross-Functional Collaboration

• For marketed products partner closely with SDIO (Strategic Data Insights & Operations), HEOR, Commercial, and Global Strategy teams to ensure integrated medical strategy & execution.
• For pipeline assets collaborate with R&D, Clinical, Regulatory, SDIO, and Commercial to support product development and launch readiness.

Innovation Leadership

• Identify and develop opportunities to differentiate the medical strategy and create new value for patients and stakeholders in underserved markets or untapped customer segments.
• Champion innovative approaches to scientific engagement, data generation, and knowledge dissemination with a goal of optimal patient outcomes.

External Engagement

• Cultivate relationships with key opinion leaders (KOLs), academic institutions, and professional societies.
• Represent the company at scientific and medical conferences, advisory boards, and external forums.

EXPERIENCE & QUALIFICATIONS:

• Advanced degree (MD, PharmD, or PhD) in a scientific discipline required.
• 15 years of progressive leadership experience in Medical Affairs within the pharmaceutical or biotech industry within the rare disease space.
• Demonstrated success in leading MSL teams, publications, and medical operations.
• Experience working in matrixed environments with strong collaboration across R&D, Commercial, and HEOR.
• Excellent communication, leadership, and interpersonal skills.

The statements in this position description are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. The manager may assign additional responsibilities and assignments from time to time.

BioCryst is an equal opportunity employer and is committed to providing equal employment opportunities without regard to age, race, religion, sex, sexual orientation, gender identity, national origin, Veterans status, disability and/or other protected class characteristics. Additionally, BioCryst is committed to achieving its business objectives in compliance with all federal, state and local law.