Scientist 3, Cell Therapy Engineering

The Opportunity

The Cell Therapy department in gRED (Genentech Research and Early Development) is looking for a motivated and inquisitive Scientist to help develop novel therapies to combat intractable diseases. We are looking for a candidate with a scientific background in cell therapy or stem cell biology, coupled with a resourceful aptitude for problem-solving. The successful applicant will display a proactive and collaborative work ethic, proficiently engaging and communicating across diverse teams with the shared goal of contributing to the Genentech cell therapy pipeline. This position will report to a Principal Scientist and play a pivotal role in shaping the growth, culture and future of the Cell Therapy Research department.

Key responsibilities

• Plan, conduct, and analyze experiments leveraging a diversity of cell types to support existing cell therapy efforts at Genentech, as well as help develop new ones

• Learn and develop new methods to efficiently produce engineered cell therapies from iPSC with controlled cellular composition

• Actively collaborate with groups both within and outside gRED, encompassing the cycle of development of successful cell therapies

• Maintain comprehensive and accurate experimental records utilizing electronic tools

• Participate and contribute to strategic planning enabling the contribution of the Cell Therapy department to Genentech's pipeline

Who You Are

• Education & Experience: A PhD with 3+ years of relevant experience, a Master's with 6+ years of experience, or a Bachelor's with 8+ years of experience

• A record of scientific contributions evidenced by co-authorship of papers, patents, or IND reports, and/or significant contribution to a gene or cell therapy pipeline

• Technical Expertise:

  • Direct experience with cell therapy or gene therapy, including construct design and functional characterization

  • A robust background in stem cell culture and engineering using a variety of gene editing modalities for knockouts and large gene insertions in ES/iPS cells and/or primary T cells

  • Experience with pooled screens or high-throughput arrayed screens

  • Working knowledge and appetite for the development of cell augmentation tools for next generation cell therapies

  • Proficiency with functional readout assays such as flow cytometry, ddPCR/qPCR, NGS, and RNA-seq

• Core Competencies:

  • An inherent team player with strong communication skills, able to prioritize team objectives and collaborate effectively

  • Strong work ethic, scientific curiosity, rigor, and a keen eye for detail

Relocation benefits are available for this posting.

The expected salary range for this position based on the primary location of California is $101,400 to $188,200. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.